node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
accC | all4257 | gene:10492953 | gene:10496306 | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.925 |
accC | alr3606 | gene:10492953 | gene:10495647 | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Dihydrolipoamide S-acetyltransferase; ORF_ID:alr3606. | 0.939 |
accC | leuA | gene:10492953 | gene:10495562 | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 2-isopropylmalate synthase; ORF_ID:alr3522; leuA gene product; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.954 |
accC | leuA-2 | gene:10492953 | gene:10496894 | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.954 |
accC | nifJ | gene:10492953 | gene:10493930 | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Pyruvate flavodoxin dehydrogenase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. | 0.948 |
accC | nifJ-2 | gene:10492953 | gene:10494837 | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Pyruvate-flavodoxin dehydrogenase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin, which reduces nitrogenase. | 0.948 |
accC | nifV2 | gene:10492953 | gene:10495004 | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Homocitrate synthase; This protein is a Fe-Mo-cofactor biosynthetic component; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.954 |
all4257 | accC | gene:10496306 | gene:10492953 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.925 |
all4257 | alr3606 | gene:10496306 | gene:10495647 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Dihydrolipoamide S-acetyltransferase; ORF_ID:alr3606. | 0.925 |
all4257 | leuA | gene:10496306 | gene:10495562 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 2-isopropylmalate synthase; ORF_ID:alr3522; leuA gene product; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.917 |
all4257 | leuA-2 | gene:10496306 | gene:10496894 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.917 |
all4257 | nifJ | gene:10496306 | gene:10493930 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Pyruvate flavodoxin dehydrogenase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. | 0.958 |
all4257 | nifJ-2 | gene:10496306 | gene:10494837 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Pyruvate-flavodoxin dehydrogenase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin, which reduces nitrogenase. | 0.958 |
all4257 | nifV2 | gene:10496306 | gene:10495004 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Homocitrate synthase; This protein is a Fe-Mo-cofactor biosynthetic component; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.917 |
alr3606 | accC | gene:10495647 | gene:10492953 | Dihydrolipoamide S-acetyltransferase; ORF_ID:alr3606. | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.939 |
alr3606 | all4257 | gene:10495647 | gene:10496306 | Dihydrolipoamide S-acetyltransferase; ORF_ID:alr3606. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.925 |
alr3606 | leuA | gene:10495647 | gene:10495562 | Dihydrolipoamide S-acetyltransferase; ORF_ID:alr3606. | 2-isopropylmalate synthase; ORF_ID:alr3522; leuA gene product; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.913 |
alr3606 | leuA-2 | gene:10495647 | gene:10496894 | Dihydrolipoamide S-acetyltransferase; ORF_ID:alr3606. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.913 |
alr3606 | leuB | gene:10495647 | gene:10493327 | Dihydrolipoamide S-acetyltransferase; ORF_ID:alr3606. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. | 0.451 |
alr3606 | nifJ | gene:10495647 | gene:10493930 | Dihydrolipoamide S-acetyltransferase; ORF_ID:alr3606. | Pyruvate flavodoxin dehydrogenase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. | 0.948 |