Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IRF2Interferon regulatory factor 2. (373 aa)    
Predicted Functional Partners:
IRF1
Interferon regulatory factor 1 isoform X1.
   
 0.865
IRF2BP2
Interferon regulatory factor 2 binding protein 2.
    
 
 0.748
IRF2BP1
Interferon regulatory factor 2 binding protein 1.
    
 
 0.748
IRF2BPL
Interferon regulatory factor 2 binding protein like.
    
 
 0.748
PCNA
Proliferating cell nuclear antigen isoform X1.
   
 
 0.710
RFC3
Replication factor C subunit 3 isoform X1.
   
 
 0.698
SPRTN
SprT-like domain-containing protein Spartan.
    
 
 0.613
CGAS
Cyclic GMP-AMP synthase.
      
 0.611
FOS
Proto-oncogene protein c-fos.
    
 
 0.585
LOC110084638
T-cell surface glycoprotein CD4-like isoform X1.
   
 
 0.582
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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