Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CDKN1CCyclin-dependent kinase inhibitor 1C. (243 aa)    
Predicted Functional Partners:
CCNE1
G1/S-specific cyclin-E1.
   
 0.983
CCND1
G1/S-specific cyclin-D1.
   
 0.983
SKP2
F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2).
    
 0.983
CCNA2
Cyclin-A2.
   
 0.981
CCNE2
G1/S-specific cyclin-E1.
   
 0.980
CCNA1
Cyclin-A1 isoform X1.
   
 0.978
CUL1
Cullin-1 isoform X1.
    
 0.977
CDK2
Cyclin-dependent kinase 2 isoform X1.
   
 0.975
SKP1
S-phase kinase-associated protein 1.
    
 0.972
CCND3
G1/S-specific cyclin-D3.
   
 0.970
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
Server load: medium (60%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.