Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
LOC110084842Cytochrome P450 11B, mitochondrial. (446 aa)    
Predicted Functional Partners:
HSD17B3
Testosterone 17beta-dehydrogenase (NADP+).
   
 0.957
LOC110076926
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase.
   
 0.956
CYP17A1
Steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase.
  
0.951
ENSPVIP00000015934
annotation not available
  
0.949
HSD11B2
Hydroxysteroid 11-beta dehydrogenase 2.
    
 0.946
CYP19A1
Aromatase.
  
 
0.942
SRD5A3
3-oxo-5-alpha-steroid 4-dehydrogenase 3 / polyprenol reductase.
     
 0.940
DHRS11
17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase.
   
 
 0.934
HSD17B2
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+).
    
 0.927
HSD11B1
Corticosteroid 11-beta-dehydrogenase isozyme 1 isoform X1.
   
 
 0.925
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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