Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PARP4Poly [ADP-ribose] polymerase 2/3/4. (459 aa)    
Predicted Functional Partners:
PARP3
Poly [ADP-ribose] polymerase 2/3/4.
     
 0.954
MVP
Major vault protein isoform X1.
   
 
 0.948
CASP7
Caspase 7.
    
 0.913
PARP1
Poly [ADP-ribose] polymerase 1.
     
 0.913
CASP9
Caspase 9.
    
 0.913
LOC110084328
Caspase-7-like.
    
 0.913
CASP3
Caspase 3.
    
 0.913
PARP2
Poly [ADP-ribose] polymerase 2 isoform X1.
     
 0.909
PARG
Poly(ADP-ribose) glycohydrolase.
    
 0.780
TEP1
Telomerase protein component 1 isoform X1.
    
 
 0.693
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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