Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GRB2Growth factor receptor-binding protein 2. (227 aa)    
Predicted Functional Partners:
SOS2
Son of sevenless homolog 2.
    
 0.999
GAB1
GRB2-associated-binding protein 1 isoform X1.
    
 0.999
SOS1
Son of sevenless homolog 1.
    
 0.998
SHC3
SHC-transforming protein 3 isoform X1.
    
 0.997
SHC1
LOW QUALITY PROTEIN: SHC-transforming protein 1.
    
 0.997
PDGFRB
Platelet-derived growth factor receptor beta.
    
 0.994
PTK2
Focal adhesion kinase 1 isoform X1.
   
 0.993
MET
Hepatocyte growth factor receptor isoform X1.
    
 0.992
KIT
Proto-oncogene tyrosine-protein kinase Kit.
   
 0.989
GAB2
Growth factor receptor bound protein 2-associated protein 2.
    
 0.988
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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