TEC protein (Pogona vitticeps) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

TEC

Tyrosine-protein kinase Tec isoform X1. (623 aa)

Predicted Functional Partners:

GRAP2

0.670

CD247

0.659

GRB2

0.630

CD3E

0.621

MET

0.611

MST1R

0.611

ZAP70

0.584

BLNK

0.576

VAV2

0.575

VAV3

0.575

Your Current Organism:

Pogona vitticeps

NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BLNK	GRAP2	ENSPVIP00000025504	ENSPVIP00000002124	B-cell linker protein isoform X1.	GRB2-related adapter protein 2 isoform X1.	0.495
BLNK	GRB2	ENSPVIP00000025504	ENSPVIP00000001151	B-cell linker protein isoform X1.	Growth factor receptor-binding protein 2.	0.952
BLNK	TEC	ENSPVIP00000025504	ENSPVIP00000001159	B-cell linker protein isoform X1.	Tyrosine-protein kinase Tec isoform X1.	0.576
BLNK	VAV2	ENSPVIP00000025504	ENSPVIP00000008121	B-cell linker protein isoform X1.	Vav guanine nucleotide exchange factor 2.	0.666
BLNK	VAV3	ENSPVIP00000025504	ENSPVIP00000008866	B-cell linker protein isoform X1.	Guanine nucleotide exchange factor VAV3.	0.666
BLNK	ZAP70	ENSPVIP00000025504	ENSPVIP00000003650	B-cell linker protein isoform X1.	Tyrosine-protein kinase ZAP-70.	0.747
CD247	CD3E	ENSPVIP00000013735	ENSPVIP00000012701	T-cell surface glycoprotein CD3 zeta chain isoform X1.	T-cell surface glycoprotein CD3 epsilon chain isoform X1.	0.998
CD247	GRAP2	ENSPVIP00000013735	ENSPVIP00000002124	T-cell surface glycoprotein CD3 zeta chain isoform X1.	GRB2-related adapter protein 2 isoform X1.	0.703
CD247	GRB2	ENSPVIP00000013735	ENSPVIP00000001151	T-cell surface glycoprotein CD3 zeta chain isoform X1.	Growth factor receptor-binding protein 2.	0.630
CD247	TEC	ENSPVIP00000013735	ENSPVIP00000001159	T-cell surface glycoprotein CD3 zeta chain isoform X1.	Tyrosine-protein kinase Tec isoform X1.	0.659
CD247	VAV2	ENSPVIP00000013735	ENSPVIP00000008121	T-cell surface glycoprotein CD3 zeta chain isoform X1.	Vav guanine nucleotide exchange factor 2.	0.444
CD247	VAV3	ENSPVIP00000013735	ENSPVIP00000008866	T-cell surface glycoprotein CD3 zeta chain isoform X1.	Guanine nucleotide exchange factor VAV3.	0.444
CD247	ZAP70	ENSPVIP00000013735	ENSPVIP00000003650	T-cell surface glycoprotein CD3 zeta chain isoform X1.	Tyrosine-protein kinase ZAP-70.	0.999
CD3E	CD247	ENSPVIP00000012701	ENSPVIP00000013735	T-cell surface glycoprotein CD3 epsilon chain isoform X1.	T-cell surface glycoprotein CD3 zeta chain isoform X1.	0.998
CD3E	GRAP2	ENSPVIP00000012701	ENSPVIP00000002124	T-cell surface glycoprotein CD3 epsilon chain isoform X1.	GRB2-related adapter protein 2 isoform X1.	0.620
CD3E	TEC	ENSPVIP00000012701	ENSPVIP00000001159	T-cell surface glycoprotein CD3 epsilon chain isoform X1.	Tyrosine-protein kinase Tec isoform X1.	0.621
CD3E	ZAP70	ENSPVIP00000012701	ENSPVIP00000003650	T-cell surface glycoprotein CD3 epsilon chain isoform X1.	Tyrosine-protein kinase ZAP-70.	0.992
GRAP2	BLNK	ENSPVIP00000002124	ENSPVIP00000025504	GRB2-related adapter protein 2 isoform X1.	B-cell linker protein isoform X1.	0.495
GRAP2	CD247	ENSPVIP00000002124	ENSPVIP00000013735	GRB2-related adapter protein 2 isoform X1.	T-cell surface glycoprotein CD3 zeta chain isoform X1.	0.703
GRAP2	CD3E	ENSPVIP00000002124	ENSPVIP00000012701	GRB2-related adapter protein 2 isoform X1.	T-cell surface glycoprotein CD3 epsilon chain isoform X1.	0.620