Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HAND2Heart- and neural crest derivatives-expressed protein 2. (153 aa)    
Predicted Functional Partners:
VCL
Vinculin isoform X1.
      
 0.849
SMYD1
Histone-lysine N-methyltransferase SMYD1 isoform X1.
    
 0.773
NKX2-5
Homeobox protein Nkx-2.5.
   
 0.760
CALHM6
Protein FAM26F.
      
 0.732
TBX20
T-box transcription factor TBX20.
   
 
 0.719
LOC110077729
Thioredoxin-like.
      
 0.694
NKX2-3
NK2 homeobox 3.
    
 0.690
GATA6
Transcription factor GATA-6 isoform X1.
   
 0.675
MYL7
Myosin regulatory light chain 2, atrial isoform.
      
 0.675
EDN1
Endothelin-1.
      
 0.660
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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