Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PLK2Serine/threonine-protein kinase PLK2. (687 aa)    
Predicted Functional Partners:
BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1.
   
 0.906
ESPL1
Separin isoform X1.
   
 0.882
CDC20B
LOW QUALITY PROTEIN: cell division cycle protein 20 homolog B.
   
 0.877
CDC20
Cell division cycle protein 20 homolog isoform X1.
   
 0.877
FZR1
Cell division cycle 20-like protein 1, cofactor of APC complex.
   
 0.877
BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta.
   
 0.860
RAD21
Double-strand-break repair protein rad21 homolog.
   
 0.859
MAD2L1
Mitotic spindle assembly checkpoint protein MAD2A.
   
 0.856
FOXM1
Forkhead box protein M1.
   
 0.848
BORA
Protein aurora borealis isoform X1.
   
 0.844
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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