Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TRIM25E3 ubiquitin/ISG15 ligase TRIM25 isoform X1. (705 aa)    
Predicted Functional Partners:
DDX58
Probable ATP-dependent RNA helicase DDX58 isoform X1.
    
  0.916
LOC110085801
E3 ubiquitin-protein ligase Midline-1-like isoform X1.
     
 
0.900
RPS27A
Ribosomal protein S27a.
    
  0.602
IFIH1
Interferon-induced helicase C domain-containing protein 1 isoform X1.
   
 0.599
UBE2N
Ubiquitin-conjugating enzyme E2 N isoform X1.
    
 0.591
SQSTM1
Sequestosome-1 isoform X1.
    
 0.528
UBC
Polyubiquitin-C.
    
  0.497
ICOS
Inducible T-cell co-stimulator.
   
 0.493
IRF3
Interferon regulatory factor 3.
   
 0.492
G3BP2
Ras GTPase-activating protein-binding protein 2 isoform X1.
   
 
 0.477
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.