Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TDRD3Tudor domain-containing protein 3. (734 aa)    
Predicted Functional Partners:
TOP3B
DNA topoisomerase III beta.
    
 0.980
FMR1
Synaptic functional regulator FMR1 isoform X1.
    
 
 0.941
WRN
Werner syndrome ATP-dependent helicase isoform X1.
   
 0.913
ENSPVIP00000020409
annotation not available
   
 0.900
FANCM
Fanconi anemia group M protein.
   
 0.900
TOP3A
DNA topoisomerase 3-alpha.
    
 0.897
MUS81
MUS81 structure-specific endonuclease subunit.
   
 0.869
RMI2
RecQ-mediated genome instability protein 2.
    
 0.856
SLX1A
Structure-specific endonuclease subunit SLX1 isoform X1.
    
 0.807
FXR2
LOW QUALITY PROTEIN: fragile X mental retardation syndrome-related protein 2.
    
 
 0.806
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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