Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCNA2Cyclin-A2. (415 aa)    
Predicted Functional Partners:
CDK1
Cyclin-dependent kinase 1.
   
 0.999
CDC6
Cell division control protein 6 homolog.
   
 0.999
FZR1
Cell division cycle 20-like protein 1, cofactor of APC complex.
   
 0.999
RB1
Retinoblastoma-associated protein.
   
 0.998
CDK2
Cyclin-dependent kinase 2 isoform X1.
   
 0.998
E2F1
Transcription factor E2F1 isoform X1.
   
 0.998
CCNA1
Cyclin-A1 isoform X1.
  
 
0.996
SKP2
F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2).
   
 0.989
CDK3
Cyclin-dependent kinase 3 isoform X1.
   
 0.988
CDT1
Chromatin licensing and DNA replication factor 1.
   
 0.988
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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