Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RBL1Retinoblastoma-like protein 1. (1006 aa)    
Predicted Functional Partners:
E2F5
Transcription factor E2F5 isoform X1.
   
 0.989
E2F4
Transcription factor E2F4 isoform X1.
   
 0.989
TFDP2
Transcription factor Dp-2 isoform X1.
   
 0.986
CCNE1
G1/S-specific cyclin-E1.
   
 0.986
CCNE2
G1/S-specific cyclin-E1.
   
 0.986
TFDP1
Transcription factor Dp-1 isoform X1.
   
 0.986
E2F1
Transcription factor E2F1 isoform X1.
   
 0.982
CCND3
G1/S-specific cyclin-D3.
    
 0.980
CCND1
G1/S-specific cyclin-D1.
    
 0.980
LOC110078878
G1/S-specific cyclin-D3-like isoform X1.
    
 0.980
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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