Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TOLLIPToll-interacting protein isoform X1. (281 aa)    
Predicted Functional Partners:
IRAK1
Interleukin-1 receptor-associated kinase 1-like.
    
 0.984
MYD88
Myeloid differentiation primary response protein MyD88.
   
 0.967
TOM1L1
TOM1-like protein 1 isoform X1.
    
 
 0.950
LOC110069865
Toll-like receptor 2.
    
 0.942
TLR2
Toll-like receptor 2.
    
 0.942
IRAK2
Interleukin-1 receptor-associated kinase-like 2 isoform X1.
    
 0.918
ENSPVIP00000020876
Toll-like receptor 2.
     
 0.903
IL1RAP
Interleukin-1 receptor accessory protein isoform X1.
    
 0.898
TIRAP
Toll-interleukin 1 receptor (TIR) domain-containing adaptor protein.
     
 0.883
MYO6
Unconventional myosin-VI isoform X1.
    
   0.865
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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