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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WNK2Serine/threonine-protein kinase WNK2 isoform X1. (2413 aa)    
Predicted Functional Partners:
LOC110071800
Ubiquitin-conjugating enzyme E2 variant 1.
   
 0.576
MIB2
E3 ubiquitin-protein ligase mind-bomb.
    
 0.533
ITSN2
Intersectin-2 isoform X1.
   
 0.508
ENSPVIP00000015452
annotation not available
   
 0.457
DDC
Dopa decarboxylase.
    
 0.456
BANK1
B-cell scaffold protein with ankyrin repeats isoform X1.
    
  0.450
SCN8A
Sodium channel protein type 8 subunit alpha isoform X1.
    
 0.447
FRA10AC1
FRA10A associated CGG repeat 1.
    
  0.443
MED27
Mediator complex subunit 27.
    
  0.443
MED16
Mediator of RNA polymerase II transcription subunit 16.
     
 0.443
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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