Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FGD3FYVE, RhoGEF and PH domain-containing protein 3 isoform X1. (784 aa)    
Predicted Functional Partners:
CDC42
Cell division control protein 42 homolog isoform X1.
   
 0.969
GNG12
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12.
     
 0.905
FGD1
FYVE, RhoGEF and PH domain-containing protein 1 isoform X1.
     
 
0.900
FGD4
FYVE, RhoGEF and PH domain-containing protein 4 isoform X1.
    
 0.581
ITSN2
Intersectin-2 isoform X1.
     
 0.500
ITSN1
Intersectin-1 isoform X1.
     
 0.493
DOCK8
Dedicator of cytokinesis protein 8 isoform X1.
   
 
 0.427
ARHGEF33
Rho guanine nucleotide exchange factor 33 isoform X1.
     
 0.415
ARHGEF1
Rho guanine nucleotide exchange factor 1.
    
 0.408
ARHGEF12
Rho guanine nucleotide exchange factor 12.
    
 0.408
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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