STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMURF1SMAD specific E3 ubiquitin protein ligase 1. (736 aa)    
Predicted Functional Partners:
SMAD7
Mothers against decapentaplegic homolog 7.
    
 0.999
SMAD6
SMAD family member 6.
    
 0.998
SMURF2
E3 ubiquitin-protein ligase SMURF2.
  
 
0.995
TGFBR1
TGF-beta receptor type-1 isoform X1.
    
 0.994
TGFBR2
TGF-beta receptor type-2.
    
 0.982
PTCH1
Protein patched homolog 1 isoform X1.
    
 0.982
SMAD5
Mothers against decapentaplegic homolog 5 isoform X1.
    
 0.980
LOC110081056
Mothers against decapentaplegic homolog 6-like.
    
 0.978
CCM2
CCM2 scaffold protein.
    
 0.977
LOC110081153
Ras homolog gene family, member A.
    
 0.975
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.