Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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Textmining
[Homology]
Score
EDEM1ER degradation-enhancing alpha-mannosidase-like protein 1. (649 aa)    
Predicted Functional Partners:
SEL1L
Protein sel-1 homolog 1.
   
 
 0.974
EDEM3
ER degradation-enhancing alpha-mannosidase-like protein 3 isoform X1.
    
0.959
EDEM2
ER degradation-enhancing alpha-mannosidase-like protein 2.
   
 
0.907
CANX
Calnexin isoform X1.
   
 
 0.859
CLGN
Calmegin.
   
 
 0.859
SEL1L2
Protein sel-1 homolog 2.
   
 
 0.833
XBP1
LOW QUALITY PROTEIN: X-box-binding protein 1.
   
 0.825
DNAJC10
DnaJ homolog subfamily C member 10 isoform X1.
    
 
 0.811
HSP90B1
Heat shock protein 90kDa beta.
    
 
 0.717
DNAJC3
DnaJ homolog subfamily C member 3.
   
 
 0.715
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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