Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DHX8ATP-dependent RNA helicase DHX8/PRP22. (1186 aa)    
Predicted Functional Partners:
CRNKL1
Crooked neck pre-mRNA splicing factor 1.
   
 0.943
CHERP
Calcium homeostasis endoplasmic reticulum protein.
   
 0.939
CACTIN
Cactin.
    
 0.935
CDC40
Pre-mRNA-processing factor 17.
   
 0.910
RBMX2
RNA-binding motif protein, X-linked 2.
   
 0.907
SLU7
Pre-mRNA-processing factor SLU7.
    
 0.907
AQR
Intron-binding protein aquarius isoform X1.
   
 0.896
CWC22
Pre-mRNA-splicing factor CWC22 homolog.
   
 0.894
XAB2
Pre-mRNA-splicing factor SYF1.
   
 0.892
NKAP
NFKB activating protein.
   
 0.888
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
Server load: low (12%) [HD]