Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
GRAP2GRB2-related adapter protein 2 isoform X1. (292 aa)    
Predicted Functional Partners:
GAB1
GRB2-associated-binding protein 1 isoform X1.
    
 0.939
GAB2
Growth factor receptor bound protein 2-associated protein 2.
    
 0.900
CSF1R
Macrophage colony-stimulating factor 1 receptor.
   
 0.881
USP8
Ubiquitin carboxyl-terminal hydrolase 8 isoform X1.
    
 
 0.879
PTPN23
Protein tyrosine phosphatase non-receptor type 23.
   
 0.874
SH2D1B
SH2 domain-containing protein 1B.
   
 0.817
FYB1
FYN binding protein 1.
   
 0.814
ZAP70
Tyrosine-protein kinase ZAP-70.
   
 0.801
PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X1.
    
 0.791
PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1.
    
 0.791
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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