Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
IMPDH1Inosine monophosphate dehydrogenase 1. (522 aa)    
Predicted Functional Partners:
GMPS
GMP synthase [glutamine-hydrolyzing] isoform X1.
 
 0.994
ATIC
Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase.
  
 0.979
ADSS2
Adenylosuccinate synthetase isozyme 2 isoform X1.
  
 
 0.975
NT5E
5'-nucleotidase.
   
 0.952
ADSS1
Adenylosuccinate synthetase isozyme 1.
  
 
 0.945
LOC110080964
Adenylosuccinate synthetase isozyme 2-like.
  
 
 0.945
NT5C2
Cytosolic purine 5'-nucleotidase isoform X1.
   
 
 0.943
AMPD3
AMP deaminase 3 isoform X1.
  
 0.941
AMPD2
AMP deaminase 2.
  
 0.940
AMPD1
AMP deaminase 1 isoform X1.
  
 0.936
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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