STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LEPLeptin. (207 aa)    
Predicted Functional Partners:
LEPR
Leptin receptor.
    
 0.999
LOC110075093
Interferon gamma-like.
   
  
 0.938
ADIPOQ
Adiponectin.
   
  
 0.925
LOC110084638
T-cell surface glycoprotein CD4-like isoform X1.
      
 0.906
INS
Insulin.
      
 0.892
POMC
Pro-opiomelanocortin isoform X1.
      
 0.890
NPY
Pro-neuropeptide Y.
      
 0.869
ESR1
Estrogen receptor isoform X1.
     
 0.830
RETN
Resistin.
   
  
 0.797
STAT3
Signal transducer and activator of transcription 3.
    
 0.777
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.