Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HSP90AB1Heat shock protein HSP 90-beta. (757 aa)    
Predicted Functional Partners:
SUGT1
Suppressor of G2 allele of SKP1.
   
 0.996
HSP90B1
Heat shock protein 90kDa beta.
  
0.985
STIP1
Stress-induced-phosphoprotein 1.
   
 0.979
PTGES3
Cytosolic prostaglandin-E synthase.
   
 0.977
FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4.
   
 0.947
HSPA4
Heat shock 70 kDa protein 4 isoform X1.
   
 0.945
RIPK1
Receptor-interacting serine/threonine-protein kinase 1 isoform X1.
    
 0.945
RIPK3
Receptor-interacting serine/threonine-protein kinase 3 isoform X1.
    
 0.939
PPP5C
Serine/threonine-protein phosphatase 5.
    
 0.933
PPID
Peptidyl-prolyl cis-trans isomerase D.
  
 0.926
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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