Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
COPS6COP9 signalosome complex subunit 6. (323 aa)    
Predicted Functional Partners:
COPS5
COP9 signalosome complex subunit 5.
   
 0.998
COPS8
COP9 signalosome subunit 8.
   
 0.996
COPS4
COP9 signalosome complex subunit 4 isoform X1.
   
 0.996
COPS2
COP9 signalosome complex subunit 2 isoform X1.
   
 0.994
GPS1
COP9 signalosome complex subunit 1 isoform X1.
   
 0.993
COPS7B
COP9 signalosome complex subunit 7b.
   
 0.986
COPS7A
COP9 signalosome complex subunit 7a isoform X1.
   
 0.985
NEDD8
Ubiquitin-like protein Nedd8.
   
 0.982
CUL1
Cullin-1 isoform X1.
    
 0.975
CUL3
Cullin-3 isoform X1.
    
 0.973
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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