Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FGF2Fibroblast growth factor 2. (99 aa)    
Predicted Functional Partners:
FGFR3
Fibroblast growth factor receptor 3 isoform X1.
   
 0.987
FGFR4
Fibroblast growth factor receptor 4.
   
 0.984
FGFR2
Fibroblast growth factor receptor 2 isoform X1.
   
 0.981
FGFR1
Fibroblast growth factor receptor 1 isoform X1.
   
 0.981
SDC1
Syndecan 1.
    
 0.951
SDC2
Syndecan-2 isoform X1.
    
 0.944
PTX3
Pentraxin-related protein PTX3.
    
 
 0.920
RET
Proto-oncogene tyrosine-protein kinase receptor Ret isoform X1.
   
 0.895
EGF
LOW QUALITY PROTEIN: pro-epidermal growth factor.
    
 0.894
PDGFRB
Platelet-derived growth factor receptor beta.
    
 0.884
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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