Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPRY1Protein sprouty homolog 1. (319 aa)    
Predicted Functional Partners:
CBL
E3 ubiquitin-protein ligase CBL.
    
 0.797
CBLB
E3 ubiquitin-protein ligase CBL-B isoform X1.
    
 0.797
CBLC
E3 ubiquitin-protein ligase CBL-C.
    
 0.797
MDFI
MyoD family inhibitor isoform X1.
    
 
 0.738
GRB2
Growth factor receptor-binding protein 2.
    
 
 0.723
RPS27A
Ribosomal protein S27a.
     
  0.696
PDGFC
Platelet-derived growth factor C isoform X1.
      
 0.695
COQ4
Coenzyme Q4.
      
 0.631
AREG
Amphiregulin.
     
  0.615
LOC110090606
Keratin-associated protein 10-2-like.
    
 
 0.613
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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