STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TOPBP1DNA topoisomerase 2-binding protein 1 isoform X1. (1494 aa)    
Predicted Functional Partners:
BRIP1
BRCA1 interacting protein C-terminal helicase 1.
   
 0.995
ATRIP
ATR interacting protein.
    
 0.993
ENSPVIP00000003246
annotation not available
    
 
 0.992
BRCA1
Breast cancer type 1 susceptibility protein.
   
 0.988
LOC110083527
LOW QUALITY PROTEIN: serine/threonine-protein kinase ATR-like.
    
 0.988
CLSPN
Claspin.
   
 0.987
BARD1
BRCA1-associated RING domain protein 1.
   
 0.986
RAD17
Cell cycle checkpoint protein RAD17 isoform X1.
   
 0.971
NBN
Nibrin isoform X1.
    
 0.969
CHEK1
Serine/threonine-protein kinase CHEK1.
   
 0.967
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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