Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARAFA-Raf proto-oncogene serine/threonine-protein kinase. (657 aa)    
Predicted Functional Partners:
BRAF
B-Raf proto-oncogene serine/threonine-protein kinase.
  
0.994
MRAS
Ras-related protein M-Ras.
    
 0.979
MAP2K2
Dual specificity mitogen-activated protein kinase kinase 2.
   
0.979
MAP2K1
Mitogen-activated protein kinase kinase 1.
   
0.979
NRAS
GTPase NRas isoform X1.
    
 0.971
LOC110078528
GTPase HRas-like.
    
 0.971
HRAS
GTPase HRas.
    
 0.971
RRAS2
Ras-related protein R-Ras2.
    
 0.957
RRAS
Ras-related protein R-Ras2.
    
 0.957
YWHAB
14-3-3 protein beta/theta/zeta.
    
 0.946
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.