Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
OTOFOtoferlin. (1948 aa)    
Predicted Functional Partners:
SLC17A8
Vesicular glutamate transporter 3.
   
 
 0.634
WFS1
Wolframin.
      
 0.565
WNT8A
Wingless-type MMTV integration site family, member 8.
      
 0.564
GLRX5
Glutaredoxin-related protein 5, mitochondrial.
      
 0.536
NFS1
Cysteine desulfurase, mitochondrial.
      
 0.479
LOC110078663
Caveolin-2-like.
   
 0.447
SRRM4
Serine/arginine repetitive matrix 4.
      
 0.437
ATP8A1
ATPase phospholipid transporting 8A1.
   
  
 0.437
RPGRIP1L
Protein fantom isoform X1.
      
 0.437
ATP8A2
Phospholipid-transporting ATPase IB.
   
  
 0.437
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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