Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PTENPhosphatase and tensin homolog. (404 aa)    
Predicted Functional Partners:
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1.
   
 0.963
LOC110082359
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like.
   
 0.963
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.
    
 0.963
PIK3CD
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1.
    
 0.962
PIK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
    
 0.958
PTK2
Focal adhesion kinase 1 isoform X1.
    
 0.957
PIK3R3
Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1.
   
 0.948
PIK3R1
Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.
   
 0.948
PIK3R2
Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta.
   
 0.948
INPP4B
Type II inositol 3,4-bisphosphate 4-phosphatase.
    
 0.944
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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