Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
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[Homology]
Score
NRASGTPase NRas isoform X1. (222 aa)    
Predicted Functional Partners:
BRAF
B-Raf proto-oncogene serine/threonine-protein kinase.
   
 0.974
RASA1
Ras GTPase-activating protein 1.
   
 0.972
ARAF
A-Raf proto-oncogene serine/threonine-protein kinase.
    
 0.971
RAF1
RAF proto-oncogene serine/threonine-protein kinase isoform X1.
    
 0.971
NF1
Neurofibromin 1.
    
 0.964
SOS1
Son of sevenless homolog 1.
   
 0.961
SOS2
Son of sevenless homolog 2.
   
 0.959
KIT
Proto-oncogene tyrosine-protein kinase Kit.
    
 0.944
RASA2
Ras GTPase-activating protein 2 isoform X1.
    
 0.944
RASSF5
Ras association domain-containing protein 5 isoform X1.
    
 0.944
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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