Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
TRIM33E3 ubiquitin-protein ligase TRIM33. (655 aa)    
Predicted Functional Partners:
ENSPVIP00000002641
annotation not available
 
      0.899
CBX3
Chromobox protein homolog 3 isoform X1.
    
 0.825
UBE2I
Ubiquitin-conjugating enzyme E2 I.
    
 0.797
ENSPVIP00000031951
annotation not available
   
 0.778
SMAD4
Mothers against decapentaplegic homolog 4 isoform X1.
   
 0.778
SETDB1
Histone-lysine N-methyltransferase SETDB1 isoform X1.
   
 0.768
ENSPVIP00000027786
annotation not available
   
 0.768
KDM1A
[histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase.
   
 
 0.765
SMARCAD1
annotation not available
   
 
 0.762
TP53
Cellular tumor antigen p53.
   
 0.708
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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