Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AP4B1AP-4 complex subunit beta-1. (739 aa)    
Predicted Functional Partners:
AP4S1
AP-4 complex subunit sigma-1.
   
 0.999
AP4E1
AP-4 complex subunit epsilon-1 isoform X1.
   
 0.999
AP4M1
AP-4 complex subunit mu-1.
   
 0.988
ITSN2
Intersectin-2 isoform X1.
    
 0.964
TEPSIN
AP-4 complex accessory subunit tepsin.
   
 
 0.960
GAK
Cyclin-G-associated kinase isoform X1.
   
 0.921
AP1M2
AP-1 complex subunit mu-2.
   
 0.892
AP1M1
AP-1 complex subunit mu-1 isoform X1.
   
 0.892
ITSN1
Intersectin-1 isoform X1.
    
 0.887
ZNF576
Zinc finger protein 576-like.
    
   0.883
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
Server load: low (20%) [HD]