Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PDLIM1PDZ and LIM domain protein 1 isoform X1. (391 aa)    
Predicted Functional Partners:
ACTN1
Alpha-actinin-1 isoform X1.
   
 
 0.712
ACTN4
Alpha-actinin-4 isoform X1.
   
 
 0.712
GFAP
Glial fibrillary acidic protein.
   
 
 0.631
SH3RF3
SH3 domain-containing RING finger protein 3 isoform X1.
    
 0.600
ACTN2
Actinin alpha 2/3.
   
 
 0.585
ACTN3
Actinin alpha 2/3.
   
 
 0.585
ADCY1
Adenylate cyclase type 1.
      
 0.541
VCL
Vinculin isoform X1.
   
 0.539
NCF2
Neutrophil cytosolic factor 2.
    
 0.514
PTK2
Focal adhesion kinase 1 isoform X1.
    
 0.482
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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