STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DTX1E3 ubiquitin-protein ligase DTX1 isoform X1. (621 aa)    
Predicted Functional Partners:
NOTCH1
Neurogenic locus notch homolog protein 1-like.
    
 0.980
NOTCH3
Notch receptor 3.
    
 0.949
ENSPVIP00000014000
Neurogenic locus notch homolog protein 4-like.
    
 0.941
ITCH
E3 ubiquitin-protein ligase Itchy homolog isoform X1.
    
 0.798
WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X1.
    
 0.730
WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2 isoform X1.
    
 0.730
RPS27A
Ribosomal protein S27a.
    
  0.552
UBC
Polyubiquitin-C.
    
 0.496
NUDCD1
NudC domain-containing protein 1 isoform X1.
    
   0.490
SMURF1
SMAD specific E3 ubiquitin protein ligase 1.
    
 0.451
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.