Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SUV39H1Histone-lysine N-methyltransferase SUV39H1 isoform X1. (414 aa)    
Predicted Functional Partners:
SIRT1
Sirtuin 1.
    
 0.947
CAMKMT
Calmodulin-lysine N-methyltransferase isoform X1.
     
 0.921
CBX3
Chromobox protein homolog 3 isoform X1.
   
 0.908
DDB1
DNA damage-binding protein 1 isoform X1.
    
 
 0.897
CBX5
Chromobox protein homolog 5 isoform X1.
   
 0.849
CBX1
Chromobox protein homolog 1.
   
 0.849
AP4E1
AP-4 complex subunit epsilon-1 isoform X1.
    
   0.838
RRP8
Ribosomal RNA processing 8.
   
 0.832
MDM2
E3 ubiquitin-protein ligase Mdm2.
    
 
 0.764
CUL4A
Cullin-4A.
    
 
 0.756
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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