Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SH2D3CSH2 domain-containing protein 3C isoform X1. (689 aa)    
Predicted Functional Partners:
BCAR1
Breast cancer anti-estrogen resistance protein 1 isoform X1.
    
 0.698
NEDD9
Enhancer of filamentation 1 isoform X1.
    
 0.695
TULP4
Tubby-related protein 4.
     
 0.601
KCNE4
LOW QUALITY PROTEIN: potassium voltage-gated channel subfamily E member 4.
     
 0.583
EFS
Embryonal Fyn-associated substrate.
    
 0.452
CASS4
Cas scaffolding protein family member 4 isoform X1.
    
 0.440
FIBCD1
Fibrinogen C domain-containing protein 1.
    
 0.435
FNBP1L
Formin binding protein 1 like.
    
 
 0.422
SLC35F2
Solute carrier family 35, member F1/2.
    
 
 0.400
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
Server load: low (22%) [HD]