STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FPGSFolylpolyglutamate synthase. (538 aa)    
Predicted Functional Partners:
DHFR
Dihydrofolate reductase isoform X1.
     
 0.935
SHMT1
Serine hydroxymethyltransferase, cytosolic isoform X1.
  
 0.927
SHMT2
Serine hydroxymethyltransferase, mitochondrial.
  
 0.927
MTHFD1L
Monofunctional C1-tetrahydrofolate synthase, mitochondrial.
  
 
 0.926
MTHFD1
Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1.
  
 
 0.926
MTHFD2
Methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase.
    
 0.921
MTHFD2L
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like.
    
 0.921
BCAT2
Branched-chain-amino-acid aminotransferase, mitochondrial isoform X1.
    
 0.917
BCAT1
Branched-chain-amino-acid aminotransferase, cytosolic isoform X1.
    
 0.917
ENSPVIP00000001738
annotation not available
     
 0.911
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.