Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HSD11B1Corticosteroid 11-beta-dehydrogenase isozyme 1 isoform X1. (291 aa)    
Predicted Functional Partners:
ENSPVIP00000015934
annotation not available
   
 0.929
CYP17A1
Steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase.
   
 0.929
LOC110084842
Cytochrome P450 11B, mitochondrial.
   
 
 0.925
LOC110076926
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase.
   
 0.914
AKR1D1
3-oxo-5-beta-steroid 4-dehydrogenase isoform X1.
   
 
 0.911
LOC110086331
UDP-glucuronosyltransferase 2C1-like.
   
 0.905
LOC110070666
UDP-glucuronosyltransferase 2A1-like.
   
 0.905
LOC110081926
Hydroxysteroid 11-beta-dehydrogenase 1-like protein B.
  
  
 
0.903
ENSPVIP00000022070
UDP-glucuronosyltransferase 1-1-like isoform X1.
   
 0.903
HSD11B1L
Hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1.
  
  
 
0.903
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
Server load: low (12%) [HD]