close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM135BFamily with sequence similarity 135 member B. (1265 aa)    
Predicted Functional Partners:
RUSC2
RUN and SH3 domain containing 2.
      
 0.563
PPP1R42
Protein phosphatase 1 regulatory subunit 42.
      
 0.561
TTC22
Tetratricopeptide repeat protein 22.
      
 0.560
LOC110080662
Protein FAM228B-like isoform X1.
      
 0.560
VPS35L
UPF0505 protein C16orf62 homolog.
   
  
 0.544
CALHM3
Calcium homeostasis modulator protein 3.
      
 0.476
KCTD18
BTB/POZ domain-containing protein KCTD18.
      
 0.473
SPATS2L
SPATS2-like protein isoform X1.
      
 0.471
FAM110A
Protein FAM110A.
      
 0.470
HDHD3
Haloacid dehalogenase-like hydrolase domain-containing protein 3.
      
 0.468
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.