Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FAM135BFamily with sequence similarity 135 member B. (1265 aa)    
Predicted Functional Partners:
RUSC2
RUN and SH3 domain containing 2.
      
 0.695
LOC110080662
Protein FAM228B-like isoform X1.
      
 0.694
PPP1R42
Protein phosphatase 1 regulatory subunit 42.
      
 0.693
VPS35L
UPF0505 protein C16orf62 homolog.
   
  
 0.639
TTC22
Tetratricopeptide repeat protein 22.
      
 0.630
FAM110A
Protein FAM110A.
      
 0.620
KLHL29
Kelch-like protein 29 isoform X1.
      
 0.615
KCTD18
BTB/POZ domain-containing protein KCTD18.
      
 0.612
PXDC1
PX domain-containing protein 1.
      
 0.608
AMZ2
Archaemetzincin-2 isoform X1.
      
 0.591
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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