Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SPRSepiapterin reductase. (242 aa)    
Predicted Functional Partners:
PAH
Phenylalanine-4-hydroxylase.
   
 
 0.991
QDPR
Dihydropteridine reductase.
   
 0.981
LOC110078745
6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase.
    
 0.978
LOC110078754
6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase.
    
 0.978
DHFR
Dihydrofolate reductase isoform X1.
     
 0.953
TPH2
Tryptophan 5-hydroxylase 2.
   
 
 0.948
TPH1
Tryptophan 5-hydroxylase 1.
   
 
 0.948
TH
Tyrosine 3-monooxygenase.
   
 
 0.933
LOC110076832
Carbonyl reductase [NADPH] 1-like.
     
 0.925
LOC110076821
Carbonyl reductase [NADPH] 1-like.
     
 0.925
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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