Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TRAF5TNF receptor-associated factor 5 isoform X1. (560 aa)    
Predicted Functional Partners:
TRAF6
TNF receptor-associated factor 6.
    
0.991
TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1.
    
 0.986
BIRC2
Baculoviral IAP repeat-containing protein 2/3.
   
 0.972
CD40
Tumor necrosis factor receptor superfamily member 5 isoform X1.
   
 0.966
TRAF2
TNF receptor associated factor 2.
    
0.966
MAP3K14
Mitogen-activated protein kinase kinase kinase 14 isoform X1.
    
 0.962
XIAP
E3 ubiquitin-protein ligase XIAP isoform X1.
   
 0.957
LOC110087544
E3 ubiquitin-protein ligase RNF31-like.
   
 0.952
LOC110085504
Receptor-interacting serine/threonine-protein kinase 2-like isoform X1.
   
 0.950
RIPK2
Receptor-interacting serine/threonine-protein kinase 2.
   
 0.950
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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