Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ADCY2Adenylate cyclase type 2 isoform X1. (984 aa)    
Predicted Functional Partners:
GNAL
Guanine nucleotide-binding protein G(olf) subunit alpha isoform X1.
   
 0.964
GNAS
Guanine nucleotide-binding protein G(s) subunit alpha isoform X1.
   
 0.964
RAPGEF4
Rap guanine nucleotide exchange factor 4 isoform X1.
   
 
 0.930
PRKACA
CAMP-dependent protein kinase catalytic subunit alpha isoform X1.
    
 0.923
PRKACB
CAMP-dependent protein kinase catalytic subunit beta isoform X1.
    
 0.923
ENTPD2
Ectonucleoside triphosphate diphosphohydrolase 2.
   
 
 0.906
NUDT2
Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical].
     
  0.900
NTPCR
Cancer-related nucleoside-triphosphatase.
     
  0.900
GNAI3
Guanine nucleotide-binding protein G(k) subunit alpha isoform X1.
   
 0.807
GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1.
   
 0.807
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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