Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
RNF40E3 ubiquitin-protein ligase bre-1-like. (891 aa)    
Predicted Functional Partners:
WAC
WW domain-containing adapter protein with coiled-coil isoform X1.
   
 0.910
CDC73
Parafibromin.
   
 0.865
LEO1
RNA polymerase-associated protein LEO1.
   
 0.865
UBE2B
Ubiquitin-conjugating enzyme E2 B.
    
 0.849
UBE2A
Ubiquitin-conjugating enzyme E2 A isoform X1.
    
 0.849
PAF1
RNA polymerase II-associated factor 1 homolog.
    
 0.846
SETD2
[histone H3]-dimethyl-L-lysine36 N-methyltransferase.
   
 
 0.827
RPS27A
Ribosomal protein S27a.
    
 0.825
CTR9
CTR9 homolog, Paf1/RNA polymerase II complex component.
   
 0.782
UBE2U
Ubiquitin-conjugating enzyme E2 U isoform X1.
    
 0.748
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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