Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
HSD17B8Hydroxysteroid 17-beta dehydrogenase 8. (310 aa)    
Predicted Functional Partners:
CBR4
Carbonyl reductase 4 / 3-oxoacyl-[acyl-carrier protein] reductase beta subunit.
  
 
0.999
HSD17B12
17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase.
 
 
 0.970
OXSM
3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial.
 
 0.959
HSD17B7
17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase.
     
 0.957
HSD17B3
Testosterone 17beta-dehydrogenase (NADP+).
 
 
 0.957
HSD17B2
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+).
  
  
 0.940
HTD2
Hydroxyacyl-thioester dehydratase type 2, mitochondrial-like.
  
 
 0.933
ENSPVIP00000030199
Cytochrome P450 family 1 subfamily B polypeptide 1.
   
 
 0.933
CYP17A1
Steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase.
   
 
 0.930
FASN
Fatty acid synthase, animal type.
  
 
 0.925
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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