STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HSD17B217beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+). (405 aa)    
Predicted Functional Partners:
HSD17B3
Testosterone 17beta-dehydrogenase (NADP+).
  
  
0.987
DHRS11
17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase.
  
 
 0.979
CYP19A1
Aromatase.
    
 0.951
SRD5A3
3-oxo-5-alpha-steroid 4-dehydrogenase 3 / polyprenol reductase.
     
 0.942
HSD17B8
Hydroxysteroid 17-beta dehydrogenase 8.
  
  
 0.940
HSD17B12
17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase.
  
  
0.938
HSD17B7
17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase.
     
 0.932
SRD5A1
3-oxo-5-alpha-steroid 4-dehydrogenase 1.
     
 0.931
SRD5A2
3-oxo-5-alpha-steroid 4-dehydrogenase 2.
     
 0.931
CYP17A1
Steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase.
   
 0.930
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.