Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PITX2Paired-like homeodomain transcription factor 2. (341 aa)    
Predicted Functional Partners:
PCNA
Proliferating cell nuclear antigen isoform X1.
      
 0.587
CTNNB1
Catenin beta-1 isoform X1.
    
 
 0.571
LRTM2
Leucine-rich repeat and transmembrane domain-containing protein 2 isoform X1.
      
 0.566
LEF1
Lymphoid enhancer binding factor 1.
    
 
 0.564
SNX16
Sorting nexin-16 isoform X1.
      
 0.551
TBX4
T-box transcription factor TBX4 isoform X1.
    
 
 0.501
LGR5
Leucine-rich repeat-containing G protein-coupled receptor 5.
      
 0.476
SIX3
Homeobox protein SIX3/6.
   
  
 0.465
SHH
Sonic hedgehog protein.
      
 0.447
WNT2B
Wingless-type MMTV integration site family, member 2.
    
 
 0.445
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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