STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ICOSInducible T-cell co-stimulator. (205 aa)    
Predicted Functional Partners:
ICOSLG
Inducible T-cell co-stimulator ligand.
   
 0.954
CD40LG
Tumor necrosis factor ligand superfamily member 5.
  
  
 0.806
CTLA4
Cytotoxic T-lymphocyte-associated protein 4.
   
  
 0.775
LOC110084638
T-cell surface glycoprotein CD4-like isoform X1.
   
  
 0.696
ENSPVIP00000019505
annotation not available
  
  
 0.690
CD40
Tumor necrosis factor receptor superfamily member 5 isoform X1.
   
  
 0.685
CD28
T-cell-specific surface glycoprotein CD28 isoform X1.
   
  
 0.639
CXCR5
C-X-C chemokine receptor type 5 isoform X1.
   
  
 0.623
TRAT1
T-cell receptor-associated transmembrane adapter 1 isoform X1.
   
  
 0.617
LOC110075093
Interferon gamma-like.
   
  
 0.614
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.