Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CTLA4Cytotoxic T-lymphocyte-associated protein 4. (196 aa)    
Predicted Functional Partners:
LOC110088482
T-lymphocyte activation antigen CD86-like isoform X1.
    
 0.940
ICOSLG
Inducible T-cell co-stimulator ligand.
     
 0.902
ICOS
Inducible T-cell co-stimulator.
   
  
 0.785
PTPN11
Tyrosine-protein phosphatase non-receptor type 11 isoform X1.
    
 0.764
ENSPVIP00000030538
Tyrosine-protein phosphatase non-receptor type 11-like isoform X1.
    
 0.764
CD40LG
Tumor necrosis factor ligand superfamily member 5.
   
  
 0.750
LAG3
Lymphocyte activation gene 3 protein isoform X1.
   
  
 0.739
LOC110075093
Interferon gamma-like.
   
  
 0.730
IL10
Interleukin-10 isoform X1.
   
  
 0.704
AP2M1
AP-2 complex subunit mu isoform X1.
    
   0.688
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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