Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
HCKTyrosine-protein kinase HCK. (501 aa)    
Predicted Functional Partners:
ZAP70
Tyrosine-protein kinase ZAP-70.
   
 0.935
CD247
T-cell surface glycoprotein CD3 zeta chain isoform X1.
   
 0.933
PTPRC
Receptor-type tyrosine-protein phosphatase C isoform X1.
   
 0.895
LYN
Tyrosine-protein kinase Lyn isoform X1.
   
 0.889
SYK
Tyrosine-protein kinase SYK isoform X1.
   
 0.877
DOK2
Docking protein 2.
   
 0.866
LOC110084638
T-cell surface glycoprotein CD4-like isoform X1.
   
 0.862
PTPN6
Tyrosine-protein phosphatase non-receptor type 6 isoform X1.
   
 0.817
CD8A
T-cell surface glycoprotein CD8 alpha chain isoform X1.
   
 
 0.812
KHDRBS1
KH domain-containing, RNA-binding, signal transduction-associated protein 1.
    
 0.808
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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